DEVELOPMENT AND EVALUATION OF FAST DISSOLVING TABLETS OF GLIMEPIRIDE
نویسندگان
چکیده
منابع مشابه
Design and Evaluation of Fast Dissolving Tablets of Clonazepam
In the present work, fast dissolving tablets of clonazepam were prepared by direct compression method with a view to enhance patient compliance. Three super-disintegrants, viz., crospovidone, croscarmellose sodium and sodium starch glycolate in different ratios with microcrystalline cellulose (Avicel PH-102) along with directly compressible mannitol (Pearlitol SD 200) to enhance mouth feel. The...
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Oral route is the most preferred route for administration of various drugs because it is regarded as safest, most convenient and economical route. Recently researcher developed the fast dissolving tablet (FDT) with improved patient compliance and convenience. FDTs are solid dosage forms which dissolve rapidly in saliva without chewing and additional water. FDTs overcome the disadvantages of con...
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The aim of this study was to prepare fast-dissolving tablets of meloxicam after its complexation with β-cyclodextrin (β-CD) and to investigate the effect of using different superdisintegrants on the disintegration and release of meloxicam from the tablets. A complex of meloxicam with β-CD was prepared by spray drying and then compressed in the form of tablets utilizing the direct compression te...
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Promethazine hydrochloride, a 5-HT3 antagonist is a powerful antiemetic drug with an oral bioavailability of 25% due to extensive hepatic first pass metabolism and is extremely bitter in taste. To overcome the above draw backs, the present study was carried out to formulate and evaluate fast dissolving taste masked wafers of Promethazine hydrochloride for sublingual administration. Taste maskin...
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ژورنال
عنوان ژورنال: Zagazig Journal of Pharmaceutical Sciences
سال: 2011
ISSN: 2356-9786
DOI: 10.21608/zjps.2011.161991